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What Are The Possible Health Effects Of Nitrate?
- Sep 26, 2017 -

Nitrate itself is not toxic, but its metabolites (such as nitrite) are of concern because of their harmful health, such as hemoglobinemia and cancer. Nitrate can be converted into nitrite in the human body, causing methemoglobinemia, and the patient's skin will be purple. Some of the population groups (for example, less than four to six months of newborn babies) and those suffering from dextrose glucose dehydrogenase deficiency are more likely to develop these symptoms. However, the nitrate content of the food for the average adult can be safe to eat. The Food and Agriculture Organization of the United Nations / World Health Organization Joint Food Additives Expert Committee (hereinafter referred to as the "Committee of Experts") in 2002 that the human intake of large amounts of nitrate may cause methemoglobinemia research evidence remains to be determined.

The International Agency for Research on Cancer (IARC) of the World Health Organization (WHO) has evaluated the carcinogenicity of nitrate and nitrite, and it is considered that nitrate or nitrites ingested from food, such as endogenous nitrification, Compounds (such as nitrosamines) can cause experimental animals to develop cancer, but show that only limited or inadequate evidence that the nitrate or nitrite in the food can cause humans and animals to develop cancer. In addition, the European Food Safety Authority (EFSA) assesses evidence based on the evidence obtained that the intake of nitrate from diets or diets does not increase the risk of cancer.

The expert committee has evaluated the safety of the nitrate and set the safety reference (ie, daily intake) to 0 to 5 milligrams per kilogram of body weight (calculated as sodium nitrate) or 0 to 3.7 milligrams per kilogram of body weight Nitrate ion calculations).